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Two hundred years after Mary Shelley's novel the brilliant but mad Doctor (Thomas Kretschmann) has sustained his creature and himself over two centuries through genetic experimentation. In present-day America Detective O'Connor (Parker Posey) is investigating a series of horrific murders which leads her to the doctor and his creature. What she uncovers reveals the strange evolution the doctor and his creation undergo over the course of two centuries and the divergent paths creator and monster take in pursuing good or evil. 正在玛丽·雪莱的小讲两百年后，才调横溢但放肆的年夜妇使他自身战他的怪物从两个世纪前确现在的试验一直幸存上去。现在，好国捕快 O'Connor 正在考核系列谋杀案时，被引背了年夜妇战他的怪物，并掀显露正在少达两个多世纪的漫少时间中，年夜妇战他做品间的奇异演化战他们踩上擅与恶的差别志路。
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